Dr. Öğr. Gör. MOHAMMED T. N. QAOUD
Eczacılık Fakültesi
E-posta
mqaoud@ciu.edu.tr
Telefon numarası
+90 392 671 11 11
Dahili
2658
Ofis
244
Diğer bilgiler
Öz geçmiş
Öğrenim Durumu
- Gazi Üni. Farmasötik Kimya (Doktora, 2023)
- Jordan Uni. of Science & Technology Farmasötik Teknoloji (Yüksek Lisans, 2017)
- Al azar Uni. Eczacılık (Lisans, 2011)
Yayınlar
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities)
- Tripeptide linked dispiro cyclotriphosphazene conjugates: Synthesis, molecular docking analysis of compounds binding within cancer cell line receptors and in vitro cytotoxic and genotoxic activities. Çalışkan, Capan, Qaoud MT et al Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2024.107621 - 2024
- Phosphazene Tripeptide Conjugates: Design, Synthesis, In Vitro Cytotoxicity and Genotoxicity, Molecular Interactions in Binding Pockets on Human Breast and Colon Cancer Cell Lines. Eray,Furkan, İrfan, Suat, Reda, Mohammed T. Qaoud, ChemMedChem. 2024. https://doi.org/10.1002/cmdc.202400570 - 2024
- Integrative bioinformatic and experimental analysis of benzoylbenzodioxol derivatives: hypoglycemic potential in diabetic mice. Hawash, Jaradat, Abualhasan, Jadallah, Fashafsheh, Zaid, Qamhia, Qneibi, Qaoud MT et al 3 Biotech. 2024 Oct;14(10):1-4. https://doi.org/10.1007/s13205-024-04103-6 - 2024
- Next-Generation Carbazole-Linked 1, 2, 4-Triazole-Thione Derivatives: Strategic Design, Synthesis, Molecular Docking, and Evaluation of Antidiabetic Potential. IrfanCapan,*MohammedHawash,MohammedT.Qaoud, and Nidal Jaradat. ACS Omega. 2024. https://doi.org/10.1021/acsomega.4c07896 - 2024
- Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents. İrfan Çapan, Mohammed Hawash, Mohammed T. Qaoud et al BMC chemistry. 2024 May 21;18(1):102. https://doi.org/10.1186/s13065-024-01207-1 - 2024
- Development of tripeptide-cyclotriphosphazene derivatives: In vitro cytotoxicity, genotoxicity studies and molecular docking analysis within ovarian and prostate cancer cell line receptors. Kaplan, Çalışkan, Çapan, Tekin, Hassan, Qaoud MT, et al Polyhedron. 2024. https://doi.org/10.1016/j.poly.2024 - 2024
- Effects of lesinurad on HEK-293 human kidney cells: In vitro and molecular docking evaluation. Tugce BORAN, Mahmoud ABUDAYYAK, Mohammed T. QAOUD Journal of Research in Pharmacy. 2024;28(3). http://dx.doi.org/10.29228/jrp.733 - 2024
- Biological, phytochemical and molecular docking characteristics of Laurus nobilis L. fresh leaves essential oil from Palestine. Jaradat, Hawash, Qaoud MT et al BMC Complementary Medicine and Therapies. 2024;24. 10.1186/s12906-024-04528-9 - 2024
- Molecular docking studies and biological evaluation of isoxazole-carboxamide derivatives as COX inhibitors and antimicrobial agents. Hawash M, Jaradat N, Abualhasan M, Qaoud MT et al 3 Biotech. 2022 Dec;12(12):342. https://doi.org/10.1007/s13205-022-03408-8 - 2023
- Anticancer activity of thiophene carboxamide derivatives as CA-4 biomimetics: Synthesis, biological potency, 3D spheroid model, and molecular dynamics simulation. Hawash M, Qaoud MT et al Biomimetics. 2022 Dec 17;7(4):247. https://doi.org/10.3390/biomimetics7040247 - 2023
- New thiazole carboxamide derivatives as COX inhibitors: design, synthesis, anticancer screening, in silico molecular docking, and ADME profile studies. Hawash M, Jaradat N, Sabobeh R, Abualhasan M, Qaoud MT. ACS omega. 2023 Aug 6;8(32):29512-26. https://doi.org/10.1021/acsomega.3c03256 - 2023
- Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors. Hawash,Jaradat,Abualhasan, Kadır Şüküroğlu, Mohammed T. Qaoud et al BMC chemistry. 2023 Mar 6;17(1):11. https://doi.org/10.1186/s13065-023-00924-3 - 2023
- Antidiabetic, antioxidant, and anti-obesity effects of phenylthio-ethyl benzoate derivatives, and molecular docking study regarding α-amylase enzyme. Jaradat N, Khasati A, Hawi M, Hawash M, Shekfeh S, Qneibi M, Eid AM, Arar M, Qaoud MT. Scientific Reports. 2022, https://doi.org/10.1038/s41598-022 - 2022
- Peroxisome proliferator-activated receptors as superior targets for treating diabetic disease, design strategies-review article. T QAOUD M, Almasri I, Önkol T. Turkish Journal of Pharmaceutical Sciences. 2022 Jun 27;19(3):353. https://doi.org/10.4274%2Ftjps.galenos.2021.70105 - 2022
- The ultrashort peptide OW: a new antibiotic adjuvant. Al Tall Y, Abualhaijaa A, Qaoud MT, Alsaggar M, Masadeh M, Alzoubi KH. Current pharmaceutical biotechnology. 2019, https://doi.org/10.2174/1389201020666190618111252 - 2019
- Antimicrobial and antibiofilm activity of UP-5, an ultrashort antimicrobial peptide designed using only arginine and biphenylalanine. Almaaytah A, Qaoud MT et al Pharmaceuticals. 2018 Jan 2;11(1):3. https://doi.org/10.3390/ph11010003 - 2018
- Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides. Almaaytah A, Qaoud MT, Abualhaijaa A, Al-Balas Q, Alzoubi KH. Infection and drug resistance. 2018, https://doi.org/10.2147/IDR.S166236 - 2018
Uluslararası diğer hakemli dergilerde yayınlanan makaleler
- Homology Modeling of Human Indoleamine-Pyrrole 2, 3-Dioxygenase-2 (hIDO2) and Virtual Screening Approaches to Identify Novel, Potent, and Selective HIDO2 Inhibitors. Mohammed Qaoud, Murat Şüküroğlu Palestinian Medical and Pharmaceutical Journal. 2023;8(3):11. https://doi.org/10.59049/2790-0231.125 - 2023
- Technical insight into biodegradable polymers used in implants. Masadeh R, Qaoud M. et al Jordan Journal of Pharmaceutical Sciences. 2018 Sep 19;11(3). https://archives.ju.edu.jo/index.php/jjps/article/view/102520 - 2018
Yönetilen Tezler
Yönetilen Doktora Tezleri
- Kimyasal modifikasyon ve sanal tarama yöntemi temelinde türetilen Procurer bileşiklerinden elde edilen yeni İndolamin-Pirrol 2,3-Dioksijenaz (hIDO) inhibitörlerinin sentezi ve biyolojik aktivitesinin araştırılması. - 2023
Yönetilen Yüksek Lisans Tezleri
- Çok etkili ultrakısa konjuge antimikrobiyal peptitlerin, planctonic ve biyofilm oluşturan metisilin dirençli Staphylococcus aureus'a karşı tasarımı. - 2017
Ödüller
- The Turkey Buslari scholarship (2018)
- DAAD Short-term research scholarship award in Biotechnology and Biomedicine center (BBZ), Leipzig- Germany (2017)
- The German Academic Exchange Service (DAAD) Scholarship (2014)
Çalışma Alanları
- İlaç tasarımı ve ADMET geliştirme, homoloji modelleme ve moleküler bağlama çalışmaları gibi alanlarda deneyimli bir araştırmacıyım. Ayrıca organik kimya konusundaki uzmanlığım, NMR ve LCMS spektrometri analizi gibi geniş kapsamlı araştırmalar içermektedir. Bunun yanı sıra, nanoteknoloji alanında da yenilikçi projelerde yer aldım. Ayrıca, günümüzün değişen patojenler dünyasında önemli bir konu olan antimikrobiyal peptit tasarımı, sentezi, analizi ve değerlendirmesine büyük bir ilgi duymaktayım. Araştırmalarım ayrıca toksisite değerlendirmesi ve MTT antiproliferatif çalışmalarının karmaşıklıklarına da inmektedir ve bu, ilaç geliştirme ve güvenliği alanına değerli bilgiler sunmaktadır. Disiplinler arası bilime derin bir ilgi duyarak, çalışmalarım moleküler görüşler ile pratik uygulamalar arasındaki boşluğu kapatmaya yönelik olarak yeni terapötik çözümlerin peşinde.